Jones notched his second career two-goal game when he tallied twice in a span of 6 1/2 minutes in the second period.
The big night by Jones gave him 13 goals, surpassing his career high set last season.
Matt Calvert also scored a shorthanded goal, as Columbus won its fourth straight game.
The Blue Jackets are on their first four-game winning streak since getting six straight wins in November and moved one point ahead of New Jersey for seventh place in the Eastern Conference with 77 points.
Sergei Bobrovsky made 22 saves after sitting out the previous two games with an illness. He allowed two goals or less for the ninth time in 11 games.
Darren Helm and Andreas Athanasiou tallied for Detroit, which is 0-5-1 in its last six games. Backup goaltender Jared Coreau made 33 saves in his second appearance of the season.
The teams traded goals 21 seconds apart in an evenly-played opening period.
Calvert finished off an odd-man rush by converting Alexander Wennberg's pass from behind the net while stationed between the circles in the high slot. Wennberg faked a shot to get Coreau out of position, circled around the net and found Calvert, who easily one-timed the pass into the vacated net.
Athanasiou scored with 3:43 remaining by putting a drive over Bobrovsky's arm. The Red Wings peppered Bobrovsky in the final minute, but the game ended when he stopped Helm's wrist shot with one second left.
--Field Level Media
Detroit | Columbus | |
Andreas Athanasiou 1 | Points | Seth Jones 2 |
Andreas Athanasiou 1 | Goals | Seth Jones 2 |
Justin Abdelkader 1 | Assists | Cam Atkinson 1 |
N/A | Power Play Goals | N/A |
N/A | Short Handed Goals | Matt Calvert 1 |
Jared Coreau .917 | Save Percentage | Sergei Bobrovsky .917 |
Jared Coreau 33 | Saves | Sergei Bobrovsky 22 |
Team | Shots | Goals | Power Play | Penalty Kill | Penalty Mins | Face Offs Won |
Detroit | 24 | 2 | 0-2 | 2-2 | 4 | 24 |
Columbus | 36 | 3 | 0-2 | 2-2 | 4 | 28 |