The Indianapolis Colts continue to have the Tennessee Titans' number.

Jacoby Brissett threw a 4-yard touchdown pass to T.Y. Hilton with 4:38 remaining to give the Colts a 19-17 win over the Titans in Nashville, Tenn., on Sunday.

It was the Colts' 14th win in the last 16 meetings between the AFC South rivals.

With Tennessee ahead 17-13 with 5 1/2 minutes to play, Colts running back Jordan Wilkins broke loose for a 55-yard run to set up first-and-goal at the Titans' 4-yard line.

Brissett then hit Hilton in the corner of the end zone on the next play to give the Colts the lead, but veteran Adam Vinatieri missed his second extra point of the game and third of the season.

After forcing Tennessee to a three-and-out, the Colts faced fourth-and-1 from their own 35 with 2:23 to play. Rather than punt, Indianapolis went for it. Brissett kept the ball on a sneak and got the first down to help the Colts kill more time.

The Titans (1-1) did get the ball back and drove to the Colts' 45-yard line with 15 seconds remaining, but an incomplete pass from Marcus Mariota intended for A.J. Brown on fourth-and-2 ended Tennessee's comeback hopes.

The Colts (1-1) took a 7-0 lead with 8:53 left in the first quarter on a 3-yard touchdown pass from Brissett to tight end Eric Ebron.

The Titans answered on the first play of the second quarter, tying the game on a 1-yard touchdown toss from Mariota to David Quessenberry.

Indianapolis regained the lead at 13-7 eight minutes before halftime on a 12-yard touchdown pass from Brissett to rookie Parris Campbell, but Vinatieri missed the PAT.

Tennessee answered with 10 straight points in the third quarter, starting with a 1-yard touchdown run by Derrick Henry with 11:31 remaining. Cairo Santos drilled a 49-yard field goal with 4:35 left in the quarter to make it 17-13.

Brissett finished the game 17 of 28 for 146 yards and three touchdowns with one interception. Mariota completed 19 of 28 passes for 154 yards and a touchdown with no interceptions.

--Field Level Media