The Stars swept the four-game season series.
The loss was the fourth in a row for Chicago, which has earned just one point -- for an overtime defeat at Calgary on Saturday -- in February.
Seguin's second goal clinched the game for Dallas, who have won four in a row and haven't lost this month. The Stars won despite being outshot by Chicago 39-30.
Jonathan Toews sent the Blackhawks to the front at the 9:07 mark of the first period when he wristed a shot past Dallas netminder Ben Bishop (37 saves). Toews rushed down the ice to snare a pass off the near boards from teammate Brent Seabrook and went high to Bishop's glove side and into the short side of the net.
It was Toews' first goal in 12 games and his 15th of the season.
Seguin tied the game with 14:16 to play in the second period when he rushed to the slot and flipped a pass from Alexander Radulov over the left shoulder of Chicago goaltender Anton Forsberg (26 saves). Dan Hamhuis was also credited with an assist on Seguin's 27th goal of the season.
Dallas took the lead less than a minute later as Stephen Johns collected the puck at the point after and fired a one-timer past Forsberg. Remi Elie and Radek Faksa earned assists.
Chicago answered at the 12:48 mark of the second period when Artem Anisimov, working on the power play, converted a rebounded shot from Seabrook into the tying goal. Vinnie Hinostroza also got an assist.
The Stars kept up their attack into the final minute of the period and found satisfaction on Tyler Pitlick's goal off a John Klingberg assist with just five seconds left, handing Dallas a 3-2 lead at the second intermission.
Dallas was to return home late Thursday to prepare for a Friday game against the Pittsburgh Penguins. The Blackhawks travel to Minnesota to face the Wild on Saturday.
--Field Level Media
Dallas | Chicago | |
Tyler Seguin 2 | Points | Brent Seabrook 2 |
Tyler Seguin 2 | Goals | Artem Anisimov 1 |
Remi Elie 1 | Assists | Brent Seabrook 2 |
N/A | Power Play Goals | Artem Anisimov 1 |
N/A | Short Handed Goals | N/A |
Ben Bishop .949 | Save Percentage | Anton Forsberg .897 |
Ben Bishop 37 | Saves | Anton Forsberg 26 |
Team | Shots | Goals | Power Play | Penalty Kill | Penalty Mins | Face Offs Won |
Dallas | 30 | 4 | 0-1 | 3-4 | 8 | 38 |
Chicago | 39 | 2 | 1-4 | 1-1 | 2 | 29 |