Yu Darvish held visiting Miami to two runs on five hits over seven innings and Steven Wilson worked his way out of a two-on, no-out jam in the ninth to pick up his first major league save Friday night as the San Diego Padres held on to defeat the Marlins 3-2.

Eric Hosmer, Matt Beaty and Manny Machado had RBI hits for the Padres.

The loss was the sixth straight for Miami, with the last five all by one run. The Padres have won eight of their last 10 games, including the first two in the four-game series against the Marlins.

With National League saves co-leader Taylor Rogers unavailable Friday, Wilson got the call as the Padres' closer. However, he gave up a leadoff single to Garrett Cooper and walked pinch hitter Jorge Soler before getting three straight flyball outs.

The only blemish against Darvish was Jesus Aguilar's two-run homer in the sixth that cut the Padres' lead to one run. Darvish didn't issue a walk and had three strikeouts while improving to 3-1. Robert Suarez struck out one in a scoreless eighth for the Padres.

For the second straight night, the Padres took a 1-0 lead in the first. Machado drew a two-out walk from Marlins starter Sandy Alcantara and came around on Hosmer's double.

The Padres made it 3-0 against Alcantara in the fifth. Trent Grisham opened the inning with a triple to right-center and scored on Beaty's double. Beaty, who was hitting .084 at the time of the hit, moved to third when C.J. Abrams reached on a throwing error by Marlins shortstop Miguel Rojas, putting Padres at first and third with no one out.

However, Alcantara retired Jake Cronenworth on a line drive to left and Ha-Seong Kim on a pop fly to third before Machado singled to left to make it 3-0.

Miami leadoff hitter Jazz Chisholm Jr. singled off Darvish to open the sixth and Aguilar followed with his third homer of the season -- a drive deep into the left field seats at Petco Park.

Darvish finished his game by retiring the last six Marlins he faced. Before Chisholm's single, Darvish had retired 11 of 12 Marlins since giving up back-to-back, two-out singles to Jon Berti and Rojas in the second.

Alcantara (2-2) allowed three runs (two earned) on five hits and two walks with five strikeouts in 4 2/3 innings.

--Field Level Media