Vladimir Guerrero Jr.'s fourth hit of the game drove in the winning run in the 10th inning and the Toronto Blue Jays defeated the visiting Baltimore Orioles 7-6 Wednesday night.

Guerrero's single against Felix Bautista (2-2) brought home automatic runner Bo Bichette with the winning run after Toronto had squandered an early 5-0 lead.

The Blue Jays have won two of the first three games of the four-game series.

Teoscar Hernandez and Matt Chapman each hit a two-run home run and Guerrero added a solo homer for Toronto.

Ryan Mountcastle had two home runs and three RBIs for Baltimore. Adley Rutschman hit his first career home run, a two-run blast, for the Orioles. The RBIs were also the first of his career.

Baltimore left-hander Bruce Zimmermann allowed six runs and 11 hits (three home runs) in 4 2/3 innings.

Toronto right-hander Jose Berrios allowed three runs and three hits while striking out eight in seven innings.

Guerrero blooped a two-out single in the first and scored on Alejandro Kirk's double.

Guerrero singled with one out in the third and Hernandez hit his fourth homer of the season with two outs. Santiago Espinal followed with a single and Chapman then hit his ninth homer of the season.

Berrios retired his first 10 batters before hitting Austin Hays with a pitch with one out in the fourth. Rutschman homered two batters later.

Guerrero led off the fifth with his 16th homer of the season to push the hosts' advantage to 6-2.

Mountcastle led off the seventh with a mammoth home run to left, and the visitors pushed across three more runs in the eighth.

Yimi Garcia replaced Berrios for the eighth and allowed two-out doubles to Cedric Mullins and Hays before Mountcastle's 12th homer tied the game at 6. Mountcastle has 12 career homers in just 28 games against Toronto.

After Bryan Baker pitched 2 1/3 hitless innings, Dillon Tate took over in the bottom of the eighth for Baltimore and pitched around a leadoff single and stolen base by Hernandez.

Jordan Romano pitched a clean top of the ninth for the Jays.

Jorge Lopez pitched a perfect bottom of the ninth.

The Orioles sacrificed automatic runner Kyle Stowers to third in the top of the 10th, but Adam Cimber (7-2) retired the next two batters.

--Field Level Media