Kyle Schwarber hit a walk-off home run in the bottom of the 10th inning to lift the Chicago Cubs to a 4-3 win over the visiting Cincinnati Reds on Tuesday night.

Schwarber's blast off Reds reliever Raisel Iglesias (2-8) landed in the basket atop the ivy-covered wall in left-center field. It was his 21st homer of the season and his third in as many games.

Robel Garcia and Kris Bryant also homered for Chicago, which rallied from a 3-0 deficit in the first inning. Anthony Rizzo finished 2-for-3 with a double.

Cubs reliever Steve Cishek (3-5) earned the victory after pitching a scoreless 10th. Cishek was one of four relievers who followed starter Alec Mills, who allowed three runs in six innings in his season debut.

Eugenio Suarez homered in a losing effort for Cincinnati, which dropped to 3-6 in extra-inning games this season.

Reds starter Anthony DeSclafani allowed three runs in 5 2/3 innings. Four relievers combined to throw 3 2/3 scoreless innings before Schwarber went deep against Iglesias.

A two-out rally allowed Cincinnati to jump to a 3-0 lead in the first inning.

Suarez started the outburst with a solo home run, his team-leading 23rd, over the wall in center field. Mills then plunked Yasiel Puig and Derek Dietrich in back-to-back plate appearances to put runners on first and second.

Nick Senzel singled to left field to score Puig. Moments later, Jose Peraza doubled to deep center to score Dietrich.

The Cubs pulled within 3-2 in the second. Rizzo led off with a single and scored on a two-run blast by Garcia -- his third homer in nine games since making his big-league debut July 3 against the Pittsburgh Pirates.

Bryant evened the score at 3 when he lofted an inside fastball into the left field bleachers with two outs in the sixth. The blast, which was Bryant's 19th, marked the end of DeSclafani's night after 87 pitches.

Veteran catcher Martin Maldonado went 0-for-4 one day after the Cubs acquired him from the Kansas City Royals for left-hander Mike Montgomery.

--Field Level Media