Wandy Rodriguez struck out 10 in seven innings while Lance Berkman and Carlos Lee homered, leading the Houston Astros to a 6-2 win over the Pittsburgh Pirates on Tuesday night.

Rodriguez (6-11) held the Pirates to one run and four hits while walking only two. The left-hander has won his last three starts.

Berkman hit a two-run homer and had three RBIs while Lee hit a solo home run.

Brad Lincoln (1-3) gave up both homers. He lasted five innings, allowing five runs and seven hits.

Berkman's RBI groundout gave Houston a first-inning lead. Lee followed with his home run. The Astros scored three in the third when Jeff Keppinger doubled in Michael Bourn before Berkman hit his home run.

Hunter Pence added an RBI double in the seventh for Houston.

Ryan Doumit's double in the fourth drove in Pittsburgh's first run. Garrett Jones added an RBI single in the eighth.

The Astros have won all four games against the Pirates this season.