Young finished with 17 points, 13 below his average, and was unable to lead the Sooners from behind in the second half.
Braxton Key hit 3-pointers on consecutive possessions to fuel a 13-0 Alabama run in the second half. Oklahoma never recovered.
Key finished with 11 points, and Herbert Jones came off the bench to provide a spark on both ends of the court for the Crimson Tide (14-7). Jones scored a career-high 14 points, grabbed five rebounds and relentlessly chased Young around the floor.
Young, who entered the game leading the nation in scoring and assists, went 6-of-17 from the floor with eight assists and five turnovers.
Alabama's Alex Reese hit a 3-pointer to ignite an 8-0 spurt, which gave the Crimson Tide a 27-15 lead midway through the first half.
Young missed his first three shots, but got going late in the first half, hitting a 3-pointer that chipped into the Alabama lead. The Crimson Tide led 41-35 at halftime.
Khadeem Lattin scored 18 points, and Brady Manek added 12 points for the Sooners (15-5), who were coming off a big win over No. 5 Kansas, but have lost three of four overall.
Led by Jones, Alabama's bench outscored Oklahoma's reserves 25-3.
The Sooners will look to bounce back Tuesday, when they return to Big 12 play and host Baylor.
The Crimson Tide were coming off a 78-66 loss to Ole Miss, which snapped a four-game win streak in the SEC, but added a signature win to their resume and set themselves up to make a push in the second half of conference play.
Alabama gets back to conference play Wednesday against Missouri.
--Field Level Media
Oklahoma | Alabama | |
Khadeem Lattin 18 | Scoring | Collin Sexton 18 |
Trae Young 8 | Assists | Dazon Ingram 3 |
Brady Manek 9 | Rebounds | Daniel Giddens 9 |
Rashard Odomes 3 | Free Throws Made | Dazon Ingram 3 |
Christian James 1 | Steals | Herbert Jones 2 |
Khadeem Lattin 2 | Blocks | Donta Hall 8 |