Ginobili was 7-for-7 from the field -- 3-for-3 from 3-point range -- in helping the Spurs claim their 10th straight win at home.
Damian Lillard scored 33 points for the Trail Blazers, who lost their third straight game. Evan Turner added 18 points and CJ McCollum 17 for Portland.
Lillard had 18 points and McCollum 13 as Portland took a 56-54 lead into intermission. Aldridge scored 14 points on 7-for-9 shooting for San Antonio, which shot .564 from the field in the first half.
San Antonio took a 66-61 early in the third quarter. The Spurs carried a 81-77 edge into the final period.
Aldridge converted a three-point play to give San Antonio a 93-87 lead with 7:29 remaining. McCollum's 17-footer cut the margin to 93-89. Ginobili followed with eight straight points -- back-to-back 3-pointers and a driving layup -- to make it 101-89 with 6:02 to play.
Jusuf Nurkic hit a layup to cut it to 101-91 with 5:24 to go, but Aldridge converted another three-point play for a 104-91 Spurs lead with 5:13 left.
Turner's three-point play brought Portland to within 104-94 with 5:02 remaining. Turner followed with a runner to make it 104-96 with 4:06 to play. Patty Mills then knocked down a three to give San Antonio a 106-96 advantage with 3:43 left. Aldridge scored on a put-back to up the lead to 108-96 with three minutes to go.
Turner scored on a drive to cut the difference to 109-98, but Kyle Anderson's driving layup hiked the Spurs' lead to 111-98. Lillard followed with a three to get the Blazers to within 111-101, but they would get no closer.
Lillard scored 11 points -- including three 3-point baskets -- to stake Portland to a 33-32 lead after one quarter.
The Blazers jumped ahead 47-41 midway through the second quarter, then settled for a two-point advantage at the half.
--Field Level Media
Portland | San Antonio | |
Damian Lillard 33 | Scoring | LaMarcus Aldridge 28 |
Damian Lillard 5 | Assists | Patty Mills 6 |
Jusuf Nurkic 12 | Rebounds | LaMarcus Aldridge 8 |
Damian Lillard 5 | Free Throws Made | Dejounte Murray 7 |
Evan Turner 2 | Steals | LaMarcus Aldridge 4 |
Jusuf Nurkic 3 | Blocks | Kyle Anderson 1 |
Team | Points | FG% | 3PM-3PA | FTM-FTA | Assists | Rebounds | Blocks | Steals | Turnovers |
Portland | 105 | 47.7 | 11-28 | 10-11 | 18 | 40 | 5 | 4 | 13 |
San Antonio | 116 | 56.0 | 7-21 | 15-21 | 21 | 36 | 3 | 12 | 8 |