Damian Lillard scored 23 points and CJ McCollum added 21 for the Trail Blazers. Portland owns its longest win streak since a 13-game skein early in the 2007-08 season.
Lou Williams went for 30 points and Montrezl Harrell chipped in 24 off the bench for the Clippers, who have lost three in a row.
All five starters scored in double figures for the Blazers. Moe Harkless scored 21 points, Jusuf Nurkic had 17 points along with 12 rebounds and four blocked shots, and Al-Farouq Aminu collected 16 points, eight rebounds and six assists.
The Blazers made 50 percent of their shots from the floor while limiting the Clippers to 44.9 percent shooting. Portland made 14 of 29 attempts from 3-point range while Los Angeles was 9 of 23 from beyond the arc.
Harkless scored 14 points and Lillard had 12 to stake the Blazers to a 58-52 lead at intermission. Williams had 13 points -- all in the second quarter -- at the break.
Portland outscored the Clippers 20-10 to start the third quarter to increase its advantage to 78-62. Los Angeles rallied with a 9-0 tear to cut the difference to 78-71. The Blazers answered with a 10-3 run to go on top 88-74.
The Clippers came back with seven straight points to make it 88-81, but Lillard hit three consecutive free throws as the Blazers carried a 91-81 lead into the fourth quarter.
The Blazers extended their edge to 105-89 early in the final period. The Clippers got no closer than 13 points the rest of the way.
Portland jumped to a 24-18 lead after one quarter. The Clippers used an 11-2 run to go ahead 31-30 midway through the period.
It was 44-44 in the second when the Blazers scored 12 in a row to take a 56-44 advantage. The Clippers answered with an 8-0 run to draw to within 56-52. Portland settled for a six-point bulge at the half.
--Field Level Media
Portland | L.A. Clippers | |
Damian Lillard 23 | Scoring | Lou Williams 30 |
Shabazz Napier 8 | Assists | Lou Williams 4 |
Jusuf Nurkic 12 | Rebounds | DeAndre Jordan 16 |
Damian Lillard 9 | Free Throws Made | Montrezl Harrell 6 |
Al-Farouq Aminu 3 | Steals | Tobias Harris 2 |
Jusuf Nurkic 4 | Blocks | Montrezl Harrell 2 |
Team | Points | FG% | 3PM-3PA | FTM-FTA | Assists | Rebounds | Blocks | Steals | Turnovers |
Portland | 122 | 50.0 | 14-29 | 16-20 | 24 | 47 | 6 | 7 | 13 |
L.A. Clippers | 109 | 44.9 | 9-23 | 20-27 | 21 | 38 | 3 | 8 | 8 |