Twins 5, Indians 4 (10): Trevor Plouffe delivered a walk-off single and Oswaldo Arcia homered among three hits as Minnesota came from behind to clip visiting Cleveland.

Left-hander Kyle Crockett (4-1) came on for the Indians in the 10th and loaded the bases on two singles and an intentional walk before striking out Kennys Vargas. Josh Tomlin came on to face Plouffe, who lined a single to center to plate Danny Santana and make a winner out of Jared Burton (3-5) in relief.

Vargas added a solo home run and Phil Hughes surrendered four runs and 10 hits in seven innings for the Twins. Michael Brantley hit his 20th home run while Trevor Bauer was reached for three runs in six frames for Cleveland, which is 4 1/2 games behind Kansas City for the second American League wild card.

Arcia’s blast to right in the third opened the scoring but Hughes gave it back in the next half inning as Cleveland rallied for two runs. David Murphy doubled and scored with two outs on a single by Lonnie Chisenhall, who moved up on the throw and scored on Mike Aviles’ single to left.

Vargas knotted it up with a home run to right in the bottom of the fourth before Brantley took Hughes’ fastball onto the concourse beyond the right-field seats in the sixth. Michael Bourn’s sacrifice fly in the seventh made it 4-2, but Arcia’s single plated Joe Mauer in the bottom of the frame and Indians shortstop Jose Ramirez failed to cleanly field a potential game-ending, double-play grounder from Aaron Hicks, allowing pinch runner Eduardo Nunez to score the tying run on the fielder’s choice in the ninth.

GAME NOTEBOOK: Indians 2B Jason Kipnis (hamstring) sat out the game and is day-to-day. … Cleveland set an American League record in the seventh inning when Marc Rzepczynski came on in relief, marking the 541st pitching change of the season for the team. … Minnesota shut down closer Glen Perkins for the rest of the season due to a left forearm strain.