BALTIMORE -- Brock Holt hit a tiebreaking three-run homer in the top of the eighth inning to give the Boston Red Sox a 7-5 victory over the Baltimore Orioles on Friday night.

Holt got his chance thanks to an error by Manny Machado with the score tied at 4. Pinch-hitter Allen Craig hit what looked like an inning-ending grounder to Machado with two outs in the eighth, but the third baseman missed it.

That allowed Pablo Sandoval to race from first to third while Craig reached. Holt followed with his three-run blast off right-hander Darren O'Day on a 1-2 pitch, giving the Red Sox (10-7) a 7-4 lead.

All three runs were unearned.

Brian Matusz (0-2) took the loss, Baltimore's fifth straight. He walked Sandoval, the only batter he faced, to start the rally.

First baseman Chris Davis homered for the Orioles in the eighth.

Alexi Ogando (1-0) got the win for Boston after escaping a bases-loaded, two-out jam in seventh. Koji Uehara came on in the ninth to post his third save. The Orioles put two on with one out, but the right-hander retired the final two batters.

The Orioles (7-10) tied it in the seventh on shortstop Everth Cabrera's sacrifice fly.

The Red Sox banged out three homers in thegame. Designated hitter David Ortiz also hit a three-run shot in the fifth off starter Miguel Gonzalez and left fielder Hanley Ramirez followed with a solo homer.

Designated hitter Jimmy Paredes hit the other Orioles' homer off starter Rick Porcello, a two-run shot in the fourth.

Porcello dominated the early innings. The right-hander struck out the first five batters and six in the first three innings. He didn't allow a hit until Machado lined a one-out single to right center in the fourth.

Paredes followed with a two-run homer to right that gave the Orioles an early 2-0 lead.

The lead did not last long as Red Sox broke out their power bats in the fifth. Ortiz and Ramirez hit back-to-back homers -- the first time the Red Sox have done that this season -- to give Boston a 4-2 lead.

Ortiz hit a three-run shot with two outs off right-hander Miguel Gonzalez, and Ramirez followed with a solo blast to left.

The Orioles cut the lead to 4-3 in the bottom of the inning on Cabrera's RBI single. That scored second baseman Rey Navarro, who had doubled for his first major-league hit and moved to third on catcher Caleb Joseph's fly ball to center.

NOTES: The Orioles placed 2B Ryan Flaherty on the 15-day disabled list, retroactive to Thursday, with a right groin strain. The team called up INF Rey Navarro from Triple-A Norfolk, and he was in the lineup Friday. ... Manager Buck Showalter will miss the game Saturday as he goes to Nashville for his father-in-law's memorial service. Bench coach John Russell will manage the team. ... After making nine errors in the first 10 games, Boston came into this series having not made an error in the past six games. ... Boston 3B Pablo Sandoval played at Oriole Park for the first time. He had played in nine games against the Orioles, but all were in San Francisco when Sandoval was with the Giants.