Titans 26, Chiefs 10: Jake Locker passed for 266 yards and two touchdowns as visiting Tennessee knocked off Kansas City.

Delanie Walker and Kendall Wright caught scoring passes as the Titans (1-0) won in the debut of new coach Ken Whisenhunt. Jason McCourty intercepted two passes and former Chiefs kicker Ryan Succop kicked four field goals.

Alex Smith was 19-of-35 for 202 yards and three interceptions for Kansas City (0-1). Star back Jamaal Charles had just 19 yards on seven carries and 15 receiving yards on four catches.

The Titans took the second-half kickoff and went 80 yards in nine plays with Locker connecting on a 6-yard scoring pass to Wright to take a 17-3 lead. McCourty’s second interception set up Succop’s 31-yard field goal and Succop kicked a 46-yarder early in the fourth to move Tennessee ahead 23-3 before the Chiefs found the end zone on Smith’s 5-yard pass to Anthony Fasano with 10:09 to play.

After a scoreless first quarter, Kansas City got on the board on a 35-yard field goal by Cairo Santos. The Titans took a 7-3 edge on Locker’s 5-yard scoring pass to Walker and Succop added a 36-yard field goal with three seconds left to give Tennessee a 10-3 halftime advantage.

GAME NOTEBOOK: The Chiefs sustained a pair of devastating injuries when LB Derrick Johnson and DE Mike DeVito each ruptured their Achilles' tendon, likely ending their seasons. ... LB Zach Brown (shoulder) will undergo an MRI exam on Monday for Tennessee, which finished with 162 rushing yards led by Shonn Greenewith 71. … Chiefs WR Dwayne Bowe served a one-game suspension for violating the league’s substance-abuse policy.