Anderson came into the game with two hits in his last 18 at-bats but produced a solid all-around game as the White Sox won for the fourth time in six games.
He hit an RBI single off Jake Odorizzi in the fourth, and two innings later, he atoned for being thrown out trying to advance on that hit.
Anderson snapped a 2-2 tie with by lining a 2-2 curveball from Ryan Pressly into left field to give Chicago a 4-2 lead. Anderson then stole third two pitches later and easily scored the fifth run on Adam Engel's sacrifice bunt, which was initially an infield single before replay overturned it.
It was Anderson's third game with at least three RBIs this season.
Anderson had a chance to add to his RBI total with runners at second and third in the eighth after left fielder Eddie Rosario misplayed Kevan Smith's fly ball for an error, but he struck out.
Yolmer Sanchez scored Chicago's other run on a sixth-inning wild pitch by Pressly.
Ehire Adrianza and Ryan LaMarre hit RBI singles for Minnesota, which lost for only the third time in its last 11 home games against Chicago and mustered two hits in the final five innings.
Rosario was 0-for-5 and is 2-for-13 since hitting three homers Sunday against the Cleveland Indians.
After Hector Santiago (2-2) allowed two runs on six hits in five innings, four White Sox relievers combined on four scoreless frames.
Jace Fry fanned Max Kepler with two on to end the seventh, and Joakim Soria got the last three outs for his sixth save in eight opportunities.
Odorizzi (3-3) allowed three runs and six hits in five-plus innings. He was lifted after allowing hits to Sanchez and Jose Abreu to start the sixth.
--Field Level Media
Chi. White Sox | Minnesota | |
Hector Santiago | Player | Jake Odorizzi |
Win | W/L | Loss |
5.0 | IP | 5.0 |
2 | Strikeouts | 7 |
6 | Hits | 6 |
3.60 | ERA | 5.40 |
Chi. White Sox | Minnesota | |
Tim Anderson | Player | Ehire Adrianza |
2 | Hits | 2 |
3 | RBI | 1 |
0 | HR | 0 |
2 | TB | 4 |
.500 | Avg | .667 |
Team | Hits | HR | TB | Avg | LOB | K | RBI | BB | SB | Errors |
Chi. White Sox | 9 | 0 | 11 | .257 | 11 | 13 | 4 | 2 | 2 | 0 |
Minnesota | 8 | 0 | 12 | .242 | 16 | 10 | 2 | 5 | 0 | 1 |