Bills 43, Jets 23: Kyle Orton threw four touchdown passes and the visiting Bills jumped out early with the help of three first-quarter interceptions by Geno Smith in a romp over the Jets.

Orton was 10-of-17 for 238 yards for the Bills (5-3), who forced six turnovers and didn't turn it over once. Rookie Sammy Watkins had three catches for 157 yards for Buffalo, which turned the ball over seven times in its previous two games.

Mike Vick was 18-of-36 for 153 yards with two fumbles and an interception for the Jets (1-7), who have lost seven straight games. Smith was 2-of-8 for five yards before getting pulled late in the first quarter and Chris Ivory scored two TDs for New York, which held Buffalo to 280 yards.

Despite four first-half turnovers, the Jets were within 24-17 at the half thanks to a pair of TDs by Ivory and a 55-yard field goal by Nick Folk as time expired. However, Vick's second fumble of the game inside the 5-yard line set up Dan Carpenter's second field goal of the third quarter for a 30-17 Bills lead.

An interception by Vick led to a 12-yard TD pass from Orton to tight end Scott Chandler early in the fourth, and Orton capped the Bills' scoring with a 61-yard TD to Watkins. Bilal Powell helped make the score respectable with a late TD run for the Jets.

GAME NOTEBOOK: The Bills are the first team with three interceptions in the first quarter since Arizona did it against Atlanta on Nov. 18, 2012. … The Bills allowed their first rushing TDs of the season. … The Jets gained seven yards in four series while Smith was in the game.