Giants 45, Redskins 14: Eli Manning threw for four touchdowns and ran for another as visiting New York throttled turnover-riddled Washington.

Manning completed 28-of-39 for 300 yards and tossed three first-half scoring passes to tight end Larry Donnell while the Giants (2-2) forced six turnovers to beat the Redskins (1-3) for the third straight time. Victor Cruz had six catches for 108 yards and Donnell added seven catches for 54 yards for New York, which has rolled up 75 points in its back-to-back wins.

Kirk Cousins committed five of Washington's turnovers in a brutal performance, finishing 19-of-33 for 257 yards and one touchdown while throwing three of his four interceptions in the third quarter. Alfred Morris rushed for 63 yards and a touchdown and running back Roy Helu had five catches for 78 yards.

Matthias Kiwanuka's sack and forced fumble set up Manning's 5-yard TD toss to Donnell before he found the tight end for 6 yards in the opening minute of the second quarter for a 14-0 lead. Cousins capped an 80-yard drive with an 18-yard strike to Andre Roberts to cut the deficit in half, but Manning and Donnell hooked up again from 6 yards out with 2:16 left in the half before Josh Brown's 29-yard field goal as time expired made it 24-7.

Washington opened the second half by marching 83 yards in five plays, capped by Morris' 20-yard burst off left tackle, but Cousins was picked off on the next two possessions and the Giants capitalized on Manning's 2-yard TD pass to tight end Daniel Fells. Trumaine McBride intercepted Cousins in the final minute of the third and Manning needed five plays to convert, running in from a yard out for a 38-14 lead with 14:07 to play.

GAME NOTEBOOK: Donnell is the first Giants tight end with three scoring passes in a game since Joe Walton in 1962 - the same year a New York quarterback last had four TD passes against Washington - while Manning notched his first rushing TD since Sept. 11, 2011 - also against the Redskins. ... Washington TE Niles Paul exited the game late in the second quarter following a helmet-to-helmet hit from Giants S Quintin Demps and was diagnosed with a concussion. Redskins LT Trent Williams suffered a right knee sprain late in the third quarter. ... Rookie running back Andre Williams rushed for 66 yards and a TD as the Giants dealt Washington its eighth consecutive NFC East defeat.