Patriots 42, Colts 20: Jonas Gray rushed for 199 yards and a franchise-record four touchdowns as visiting New England cruised to its sixth consecutive victory.

Tom Brady took a backseat to Gray, who carried the ball 38 times in his fourth career game as the Patriots (8-2) amassed 244 yards rushing and scored touchdowns on its first four second-half possessions. Bray finished 19-of-30 for 257 yards with two touchdowns and two interceptions while tight end Rob Gronkowski added four catches for 71 yards and a score as New England dominated the matchup of AFC division leaders.

Andrew Luck (23-of-39, 303 yards) extended his string of 300-yard games to eight while throwing for two touchdowns and one pick as the Colts (6-4) lost for the second time in three games following a five-game winning streak. Tight end Coby Fleener had seven catches for 144 yards for Indianapolis, which managed only 19 yards on the ground.

A pair of short scoring runs by Gray built a 14-3 lead, but Brady was picked off by Mike Adams with 76 seconds left in the half and Luck needed three plays to cash in, floating a 10-yard pass to Hakeem Nicks in the left corner of the end zone to cut the deficit to 14-10 at the half. New England took the opening kickoff of the second half 80 yards in eight plays, capped by a 2-yard pass to tight end Tim Wright, before Adam Vinatieri booted a 53-yarder on the ensuing drive.

The Patriots went 80 yards on the next possession before Gray bulled in from the 2 for a 28-13 edge but Luck brought the Colts right back with a 1-yard pass to offensive lineman Anthony Castonzo with 13 1/2 minutes to play. The Patriots made it three straight 80-yard touchdown drives when Gray plowed in from 1 yard for a 35-20 lead with 8:43 remaining before Brady tossed a 25-yard scoring strike to Gronkowski two minutes later to break it open.

GAME NOTEBOOK: New England is averaging 40.5 points during its winning streak to move one game ahead of Denver and Kansas CIty for the AFC's best record. ... Luck is one game shy of Drew Brees' NFL record of nine straight 300-yard games while Vinatieri became the first player in NFL annals to register 17 straight 100-point seasons and tied Mike Vanderjagt for second on the franchise all-time list with his 28th consecutive field goal. ... Colts RB Ahmad Bradshaw exited in the fourth quarter with an injury to his lower leg while TE Dwayne Allen was carted off in the first half with an ankle injury. ... Gronkowski moved into second place on the team's all-time list with his 51st TD.