Embiid recorded his 22nd game of at least 20 points and 10 rebounds.
Ben Simmons added 17 points, JJ Redick contributed 16 and Marco Belinelli had 15 for the Sixers, who won their seventh in a row.
Robert Covington also scored 12 points, and Dario Saric had 11.
The Sixers also won 10 straight at home for the first time since 2002-03 in coach Larry Brown's final season.
Aaron Gordon led the Magic with 20 points while Evan Fournier added 16 and Nikola Vucevic had 15. Mario Hezonja also had 13.
Philadelphia was cruising and even received a rare 3-pointer from Trevor Booker to give it a 95-75 lead early in the fourth. It was only Booker's fifth trey all season and just his second as a member of the Sixers.
The 20-point lead was more than enough for the Sixers to hold on, though it wasn't always pretty down the stretch.
Orlando did manage to get within 11 at 108-97 with 3:22 left following a 13-2 run.
Hezonja hit a pair of free throws with 2:15 remaining and suddenly the lead was sliced to 108-99.
Belinelli came back with a clutch jumper to put Philadelphia back up 110-99.
Timothe Luwawu-Cabarrot also added a big basket for a 112-101 advantage with 1:01 left.
The Sixers held an 87-71 lead after the third when T.J. McConnell's layup landed through the net at the buzzer.
Belinelli's nifty driving layup gave the Sixers a 51-33 lead with 3:46 left in the first half. Covington followed with his fourth 3-pointer and a commanding 54-33 advantage.
On the Sixers' next possession, Simmons dropped in a right-handed hook to cap a 10-0 run and push their lead to 56-33.
The Sixers led 58-40 at halftime thanks in large part to Embiid's 19 points and eight rebounds.
Orlando held an early nine-point lead before the Sixers' surge began.
--Field Level Media
Orlando | Philadelphia | |
Aaron Gordon 20 | Scoring | Joel Embiid 28 |
Aaron Gordon 7 | Assists | Ben Simmons 7 |
Nikola Vucevic 9 | Rebounds | Joel Embiid 14 |
Evan Fournier 5 | Free Throws Made | Joel Embiid 7 |
Mario Hezonja 3 | Steals | T.J. McConnell 2 |
Nikola Vucevic 2 | Blocks | Marco Belinelli 1 |
Team | Points | FG% | 3PM-3PA | FTM-FTA | Assists | Rebounds | Blocks | Steals | Turnovers |
Orlando | 105 | 44.7 | 13-31 | 16-19 | 27 | 33 | 5 | 7 | 13 |
Philadelphia | 116 | 51.9 | 9-27 | 23-27 | 31 | 45 | 4 | 5 | 14 |