TORONTO -- Yasmany Tomas and Peter O'Brien hit home runs, Patrick Corbin pitched into the seventh inning and the Arizona Diamondbacks defeated the Toronto Blue Jays 4-2 on Tuesday night.

Corbin (4-6) allowed eight hits, three walks and two runs in 6 1/3 innings. The left-hander struck out three as the Diamondbacks (34-39) extended their winning streak to five games and the Blue Jays (39-34) lost their third in a row.

Blue Jays starter Marco Estrada (5-3) allowed two hits, including a home run, three walks and three runs while striking out eight in six innings before Jesse Chavez replaced him. It was the 11th straight start in which Estrada had allowed five or fewer hits while going six or more innings.

O'Brien hit his fourth homer of the season with one out in the seventh to give the Diamondbacks a 4-2 lead.

The Blue Jays threatened in the bottom of the seventh when Ezequiel Carrera walked with one out and Devon Travis extended his hitting streak to eight games with a single that put runners at the corners. Jake Barrett replaced Corbin and ended the inning on a double-play grounder to second by Josh Donaldson.

Toronto's Jason Grilli and Arizona's Tyler Clippard each pitched a perfect eighth.

After Toronto's Roberton Osuna struck out the side in the top of the ninth, Arizona's Daniel Hudson pitched a 1-2-3 bottom of the ninth to post his first save of the season.

Arizona scored first. Jean Segura accepted his second walk of the game with two outs in the top of the third. He stole second base for the second time of the game and came home when Chris Hermann grounded a single to left for the Diamondbacks' first hit of the game.

The Blue Jays had runners at the corners in the bottom of the third after a one-out single by Carrera and a two-out hit by Donaldson. Corbin induced an inning-ending grounder to third from Edwin Encarnacion.

The Diamondbacks took a 3-0 lead in the fourth on the 10th homer of the season by Tomas, a blast to left that followed a one-out walk to Robbie Weeks Jr. Center fielder Kevin Pillar saved further damage when he made a superb catch at the wall on a drive by O'Brien.

Pillar hit a two-run double to left center in the bottom of the fourth to cut the lead to 3-2. It scored Michael Saunders, who had doubled with one out, and Troy Tulowitzki, who had walked.

NOTES: Blue Jays LHP Brett Cecil (triceps) and LHP Franklin Morales (shoulder) were scheduled to begin their rehabilitation assignments with Class-A Dunedin on Tuesday. ... Toronto RF Jose Bautista (left big toe) has been diagnosed by specialists with turf toe and will wear a walking boot for two weeks and then will be re-evaluated. He was put on the disabled list Friday. ... The Diamondbacks were making only their second visit to Toronto. The other one was in 2004. ... Arizona used INF/OF Rickie Weeks Jr., as the designated hitter Tuesday. ... Arizona LHP Robbie Ray (4-5, 4.44 ERA) will face LHP J.A. Happ (8-3, 3.41) in the series finale on Wednesday afternoon.