MINNEAPOLIS -- Quiet for eight innings in his return to Target Field, Toronto Blue Jays left fielder Chris Colabello made his presence known in a big way in his first game back against his former team.

Colabello's two-run homer in the ninth inning broke a tie and the Blue Jays defeated Minnesota 6-4 on Friday night, snapping the Twins' five-game winning streak.

Waived by Minnesota last winter and claimed by the Blue Jays, Colabello has been on a tear for the better part of a month. Playing against the club that gave him his first chance in the big leagues, Colabello hammered a first-pitch fastball from Twins closer Glen Perkins into the bullpens in left center field for his fourth homer of the season.

"(Perkins) is going to challenge, I've seen him pitch for a couple years now," Colabello said. "I was looking heater, trying to stay aggressive. You don't want to get behind a guy like him and it was down a little bit, but I put a good swing on it.

"First at-bat, I got a lot more jittery than I expected to. But as the game went on, I think I settled in. I couldn't have drawn it up that way, but I'm really glad it happened."

Colabello's timely blast made a winner of Blue Jays left-hander Mark Buehrle, who was bashed for four runs and five hits in the first inning before settling in.

Colabello (6-4) gave up only one hit in the final eight innings while facing the minimum. His final line: Four runs, six hits, no walks with three strikeouts.

"I felt too good. Everything was up," Buehrle said. "I've had plenty of games where I've given up a lot of runs early in a game and settled down and went deep in the game.

"I think I was one more batter away from being taken out and going two-thirds of an inning. I didn't change anything, I think it was a lot of luck after the first inning."

For Buerhle, it was his 29th career win over Minnesota, the most for him against any opponent and the most by an opponent against the Twins in club history.

After the first inning, it didn't look like Buehrle's night would last long.

The first three hitters to face him reached and Twins first baseman Joe Mauer's RBI single gave Minnesota a 1-0 lead only three batters into the game.

Right fielder Torii Hunter followed with an RBI double, catcher Kurt Suzuki a run-scoring single and designated hitter Eduardo Escobar with a sacrifice fly, giving the Twins a 4-0 lead after the first.

But Toronto scored the final six runs of the game, highlighted by a three-run homer by third baseman Josh Donaldson in the fifth that evened the score at 4.

Donaldson has homered in four consecutive games and has five home runs during that span. His 14 homers this season are tied for second in the American League, four behind Seattle's Nelson Cruz.

"He's just strong. He can miss balls and hit them a long way. He keeps his hands back well. You've just got to mix it up and go with your best stuff," Twins starter Trevor May said.

"I'm not unhappy with the pitch choice. I'm definitely unhappy with the pitch location. I think a changeup down would have benefited me a little bit better. I knew he was going to be aggressive there early in the count. That seems to be something they do a lot."

May didn't figure into the decision, allowing four runs, eight hits and a walk in six innings. Perkins took the loss, giving up two runs in one inning, the first time this season that he has allowed more than one run.

Minnesota couldn't muster much of anything against Buehrle, getting a one-out single from third baseman Trevor Plouffe in the sixth. But he was erased one batter later on a 6-4-3 double play by Hunter.

"Frustrating to lose a game when you get four in the first inning off a guy like that," Twins manager Paul Molitor said. "As we know that he can, he settled in. A complete game after that start, tha