TORONTO -- Right-hander Drew Hutchison allowed two runs in eight innings, and third baseman Josh Donaldson hit a two-run homer as the Toronto Blue Jays held on to defeat the Baltimore Orioles 7-6 Thursday and sweep a three-game series.

Orioles third baseman Manny Machado drove in four runs with two home runs, including a three-run blast against right-hander Miguel Castro in Baltimore's four-run ninth that trimmed the lead to one.

Right fielder Kevin Pillar also drove in two runs for the Blue Jays, who handed the Orioles (7-9) their fourth straight loss. Toronto (9-7) completed a 5-5 homestand.

The Blue Jays won for the fifth time in the first six meetings with the Orioles this season.

Hutchison (2-0) allowed four hits, including a home run by Machado, and no walks while striking out seven.

Toronto right-hander Liam Hendriks took over in the ninth, and he allowed three singles to four batters. He exited with one run in, two runners on and one out. Castro was greeted by Machado's second homer of the game and third of the season.

Castro finished the inning to pick up his fourth save.

Orioles right-hander Chris Tillman (2-2) allowed five hits, including Donaldson's home run, five walks and seven runs in 4 1/3 innings.

Hutchison retired the first 15 batters of the game before Machado hit the first pitch of the sixth for a homer to left field. The blast cut Toronto's lead to 7-1.

The Blue Jays scored three runs in the third inning, two of them on the fourth home run of the season by Donaldson.

Left fielder Danny Valencia led off with a walk and right fielder Kevin Pillar hit an infield single behind the bag at third base. Shortstop Jose Reyes sacrificed the runners to second and third.

Second baseman Devon Travis hit a fielder's choice grounder to first baseman Chris Davis. Valencia scored as the ball got away from catcher Ryan Lavarnway, who retrieved it in time to tag Pillar, who also tried to score. Donaldson homered on a 1-0 pitch to put Toronto into a 3-0 lead.

Valencia's one-out double followed walks to first baseman Justin Smoak and catcher Russell Martin to bump the lead to 4-0. Pillar doubled off the bag at third to score two more runs.

Tillman was replaced by right-hander Brad Brach in the fifth after allowing Donaldson's leadoff double and a one-out walk to Smoak. Martin greeted Brach with a double to score Donaldson for a 7-0 lead.

The Orioles scored a run in the seventh. Center fielder Adam Jones led off with a double and right fielder Delmon Young singled with one out. Jones scored from third when designated hitter Travis Snider forced Young at second with a grounder to Hutchison. Snider had two RBIs on the game.

NOTES: Toronto put C Dioner Navarro (left hamstring strain) on the 15-day disabled list and recalled C Josh Thole from Triple-A Buffalo. Navarro was injured trying for a double in the seventh inning of Tuesday's 13-6 win over Baltimore. ... OF Alejandro De Aza and INF Ryan Flaherty were out of the Orioles' starting lineup Thursday. OF David Lough played left field and INF Jimmy Paredes was at second base. Flaherty has a groin injury, but De Aza is not injured. ... The Orioles open a three-game series against the Boston Red Sox on Friday at Camden Yards. RHP Miguel Gonzalez (2-1, 2.55 ERA) will face Red Sox RHP Rick Porcello (1-2, 6.63 ERA). ... The Blue Jays start a 10-game trip Friday at Tropicana Field with RHP R.A. Dickey (0-1, 3.26 ERA) facing Tampa Bay Rays LHP Drew Smyly (season debut) in the opener of a three-game series.