National Football League
MATCHUP
San Francisco (5-6-0) at Buffalo (9-2-0)
| Stats: | Overall | Home/Away | Last 3 | Grass/Turf | Last 3 Home/Away |
|---|---|
| Records: | ATS | Over/Under |
| Teams: | San Francisco 49ers | Buffalo Bills |
Summary
| 8:20 PM ET | W‑L | ATS | H | A | AF | AA | O/U |
|---|---|---|---|---|---|---|---|
| San Francisco | 5-6 | 4-7-0 | 3-3 | 2-3 | 23.6 | 23.6 | 6-5-0 |
| Buffalo | 9-2 | 7-4-0 | 5-0 | 4-2 | 29.1 | 19.5 | 7-4-0 |
Live Odds | All Odds
| Home | O/U | |
| Opening line | 2 -110 | 47 -110 |
| FanDuel | -6.5 -105 | 44.5 -109 |
| Westgate | -6.5 -108 | 44.5 -110 |
| Wynn | -6.5 -110 | 45.5 -110 |
| Best home line | Recent line moves |
Recent Trends
| San Francisco: |
|
| Buffalo: |
|
Quickchart Matchup
 San Francisco Off vs
 Buffalo Def |
|---|
|
384.5 yards
329.1 yards
4.9 yards/rush
4.9 yards/rush
8.1 yards/attempt
6.2 yards/attempt |
|
Buffalo Off vs
San Francisco Def |
|---|
|
345.3 yards
304.3 yards
4.3 yards/rush
4.2 yards/rush
7.3 yards/attempt
6.2 yards/attempt |
Quarterbacks
| San Francisco | Yds | Comp % | Y/A | TD/Int | Rate |
|---|---|---|---|---|---|
| B. Purdy | 2613 | 66.01 | 8.5 | 13/8 | 95.9 |
| B. Allen | 199 | 58.62 | 6.9 | 1/1 | 76.7 |
| J. Dobbs | 0 | 0.00 | 0.0 | 0/0 | - |
| Buffalo | Yds | Comp % | Y/A | TD/Int | Rate |
|---|---|---|---|---|---|
| J. Allen | 2543 | 64.01 | 7.5 | 18/5 | 98.2 |
| M. Trubisky | 5 | 66.67 | 1.7 | 0/0 | 70.1 |
| S. Buechele | 0 | 0.00 | 0.0 | 0/0 | - |
| M. White | 0 | 0.00 | 0.0 | 0/0 | - |
ATS Records | In Depth
| W‑L | ATS | H | A | Grass | Turf | |
|---|---|---|---|---|---|---|
|
SF BUF |
5‑6 9‑2 |
4‑7‑0 7‑4‑0 |
3‑3‑0 3‑2‑0 |
1‑4‑0 4‑2‑0 |
3‑5‑0 1‑0‑0 |
1‑2‑0 6‑4‑0 |
Overall Stats | In Depth
| Off | Avg | Yards | Pass | Rush | Y/R | Y/A |
|---|---|---|---|---|---|---|
|
SF BUF |
23.6 29.1 |
384.5 345.3 |
246.2 226.1 |
138.4 119.2 |
4.9 4.3 |
8.1 7.3 |
| Def | Avg | Yards | Pass | Rush | Y/R | Y/A |
|
SF BUF |
23.6 19.5 |
304.3 329.1 |
193.5 210.0 |
110.8 119.1 |
4.2 4.9 |
6.2 6.2 |
Home/Away Stats |
In Depth |
Last 3 H/A
| Off | Avg | Yards | Pass | Rush | Y/R | Y/A |
|---|---|---|---|---|---|---|
|
SF BUF |
22.0 35.0 |
391.6 364.0 |
274.4 259.2 |
117.2 104.8 |
4.5 4.0 |
8.6 7.8 |
| Def | Avg | Yards | Pass | Rush | Y/R | Y/A |
|
SF BUF |
26.4 19.2 |
319.4 286.0 |
204.4 179.6 |
115.0 106.4 |
4.1 4.7 |
6.6 5.0 |
Over/Under Records | In Depth
| O/U | H | A | Grass | Turf | Tot | |
|---|---|---|---|---|---|---|
|
SF BUF |
6-5-0 7-4-0 |
3-3-0 5-0-0 |
3-2-0 2-4-0 |
4-4-0 0-1-0 |
2-1-0 7-3-0 |
47.3 48.5 |
Last 3 Stats | In Depth
| Off | Avg | Yards | Pass | Rush | Y/R | Y/A |
|---|---|---|---|---|---|---|
|
SF BUF |
16.7 30.0 |
310.3 368.7 |
227.0 257.7 |
83.3 111.0 |
3.8 4.1 |
7.3 6.7 |
| Def | Avg | Yards | Pass | Rush | Y/R | Y/A |
|
SF BUF |
26.0 22.7 |
276.3 331.0 |
152.0 215.0 |
124.3 116.0 |
4.1 5.0 |
5.4 6.7 |
Grass/Turf Stats | In Depth
| Off | Avg | Yards | Pass | Rush | Y/R | Y/A |
|---|---|---|---|---|---|---|
|
SF BUF |
25.7 28.9 |
434.7 355.1 |
279.0 234.8 |
155.7 120.3 |
5.1 4.3 |
8.9 7.3 |
| Def | Avg | Yards | Pass | Rush | Y/R | Y/A |
|
SF BUF |
24.7 20.4 |
352.3 326.9 |
253.7 209.8 |
98.7 117.1 |
4.2 5.0 |
7.3 6.3 |
Injuries
San Francisco
| Player | Status/Updated | Notes | |
|---|---|---|---|
| Deommodore Lenoir | DB | Questionable - Knee - 11/26/24 | Lenoir is dealing with a knee injury, and it is unknown if he will play against the Bills on Sunday, December 01st. |
| Dominick Puni | OL | Questionable - Shoulder - 11/26/24 | Puni is nursing with a shoulder injury, and it is unclear if he will play against the Bills on Sunday, December 1st. |
| Demetrius Flannigan-Fowles | LB | Questionable - Knee - 11/25/24 | Flannigan-Fowles is dealing with a knee injury, and it remains to be seen if he will be active against the Bills on Sunday, December 1st. |
| Jordan Elliott | DL | Questionable - Concussion - 11/25/24 | Elliott is managing concussion, and it is up in the air if he will suit up against the Bills on Sunday, December 1st. |
| Renardo Green | CB | Questionable - Neck - 11/25/24 | Green is bothered by a neck injury, and it remains to be seen if he will be active against the Bills on Sunday, December 1st. |
| Jacob Cowing | WR | Questionable - Concussion - 11/24/24 | Cowing is hampered by concussion, and it is uncertain if he will play against the Bills on Sunday, December 1st. |
| Nick Bosa | DL | Questionable - Hip - 11/24/24 | Bosa is dealing a hip injury, and it is uncertain if he will play against the Bills on Sunday, December 1st. |
| Brock Purdy | QB | Questionable - Shoulder - 11/24/24 | Purdy is dealing with a sore right shoulder, and it is unclear if he will play against the Bills on Sunday, December 1st. |
| Trent Williams | OT | Questionable - Ankle - 12/1/24 | Williams is laid up with an ankle injury, and it is unknown if he will play against the Bears on Sunday, December 8th. |
| Aaron Banks | OL | Questionable - Thigh - 12/1/24 | Banks is nursing with a thigh injury, and it is uncertain if he will play against the Bears on Sunday, December 8th. |
| Charvarius Ward | CB | Questionable - Personal - 11/24/24 | Ward has been sidelined due to a personal reason, and it is uncertain if he will play against the Bills on Sunday, December 1st. |
| Kevin Givens | DL | Questionable - Groin - 11/24/24 | Givens is nursing a groin injury, and it is uncertain if he will play against the Bills on Sunday, December 1st. |
| Javon Hargrave | DL | out for season - Tricep - 9/23/24 | Hargrave is sidelined due to a partial triceps tear, and he is expected to miss the remainder of the season. |
| Tatum Bethune | LB | Out indefinitely - Knee - 11/25/24 | Bethune has been placed on injured reserve with a Knee - MCL injury, and he will miss an undetermined length of time. |
| Darrell Luter Jr. | CB | Out indefinitely - Pelvis - 11/17/24 | Luter Jr is placed on the injured reserve list with a pelvis injury, and he is without a definitive timetable for return. |
| Mitch Wishnowsky | P | Out indefinitely - Back - 11/17/24 | Wishnowsky is placed on the injured reserve list with a back injury, and it is unknown how long he will be debilitated. |
| Brandon Aiyuk | WR | Out indefinitely - Knee - 10/23/24 | Aiyuk is dealing with a torn ACL, and his return is unknown. |
| Talanoa Hufanga | S | Out indefinitely - Wrist - 10/9/24 | Hufanga has been placed on injured reserve with a wrist injury, and he will miss an extended period. |
| Curtis Robinson | LB | out for season - Knee - 9/29/24 | Robinson is placed on the injured reserve list with a knee injury, and he has been shut down for the remainder of the season. |
| Dre Greenlaw | LB | Out indefinitely - Achilles - 10/7/24 | Greenlaw has been placed on the PUP list while he recovers from an achilles injury, and he is without a definitive timetable for recovery. |
| Elijah Mitchell | RB | out for season - Undisclosed - 10/1/24 | Mitchell has been placed on the IR due to an undisclosed injury, and he will miss the entire season. |
| Jon Feliciano | OL | Out indefinitely - Knee - 10/7/24 | Feliciano is battling with a knee injury, and it is unknown how long he will be debilitated. |
| Ambry Thomas | CB | Out indefinitely - Forearm - 8/31/24 | Thomas will miss an extended period due to broken right forearm, a timetable for recovery has yet to be established. |
| Drake Jackson | DL | out for season - Knee - 10/8/24 | Jackson is out of action due to a knee injury, and he will be idle for the remainder of the season. |
Buffalo
| Player | Status/Updated | Notes | |
|---|---|---|---|
| Spencer Brown | OT | Questionable - Ankle - 11/17/24 | Brown is hobbled by an ankle injury, and it has yet to be established if he will play against the 49ers on Sunday, December 1st. |
| Dalton Kincaid | TE | Questionable - Knee - 12/1/24 | Kincaid missed the previous two contests due to a knee injury, and it has yet to be established if he will play against the Rams on Sunday, December 8th. |
| Keon Coleman | WR | Questionable - Wrist - 11/17/24 | Coleman is dealing with a right wrist injury, and it has yet to be established if he will play against the 49ers on Sunday, December 1st. |
| Kaiir Elam | CB | Questionable - Shoulder - 11/17/24 | Elam is laid up with a shoulder injury, and it is unclear if he will play against the 49ers on Sunday, December 1st. |
| Connor McGovern | G | Questionable - Shoulder - 11/17/24 | McGovern is hobbled by a shoulder injury, and it is uncertain if he will play against the 49ers on Sunday, December 1st. |
| Reggie Gilliam | FB | Questionable - Hip - 11/17/24 | Giliam is battling a hip injury, and it is undetermined if he will play against the 49ers on Sunday, December 1st. |
| Matt Milano | LB | Questionable - Bicep - 11/30/24 | Milano has been activated from the injured reserve list with torn biceps, and it is undetermined if he will play against the 49ers on Sunday, December 1st. |
| Baylon Spector | LB | Out Indefinitely - Calf - 11/9/24 | Spector has been placed on injured reserve with a calf injury, and he will miss an undetermined length of time. |
| Dawuane Smoot | DE | Out indefinitely - Wrist - 11/5/24 | Smoot is placed on the injured reserve list with a wrist injury, and it is unclear how long he will be debilitated. |
| DeWayne Carter | DT | Out indefinitely - Wrist - 10/27/24 | Carter has been placed on the injured reserve list due to wrist injury , and he will miss an extended period. |
| Tylan Grable | OT | Out indefinitely - Abdominal - 9/26/24 | Grable has been placed on injured reserve due to an abdominal injury, and he will miss an undetermined length of time. |
| Tommy Doyle | OT | Out indefinitely - Knee - 9/13/24 | Doyle has been placed on the PUP list while he recovers from a knee injury, and there is no timetable for his return. |
| Travis Clayton | OT | Out indefinitely - Shoulder - 9/9/24 | Clayton is hampered by a shoulder injury, and it has yet to be determined if he will return to action. |
| Shane Buechele | QB | Out indefinitely - Neck - 8/13/24 | Buechele is out of action due to a neck injury, and it is unclear when he will return in action. |
Recent Meetings
| San Francisco | Buffalo | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Date | Away/Home | Line | ATS | Tot | Rus | Pas | Tot | Rus | Pas | |
| 12/7/20 | BUF (34) - SF (24) | -1.5/48 | BUF/O | 402 | 86 | 316 | 449 | 81 | 368 | |
| 10/16/16 | SF (16) - BUF (45) | -7.5/44 | BUF/O | 300 | 133 | 167 | 492 | 313 | 179 | |
| 10/7/12 | BUF (3) - SF (45) | -10/45.5 | SF/O | 621 | 311 | 310 | 204 | 89 | 115 | |
| 11/30/08 | SF (10) - BUF (3) | -6.5/43 | SF/U | 195 | 62 | 133 | 350 | 156 | 194 | |
| 12/26/04 | BUF (41) - SF (7) | 11/42.5 | BUF/O | 189 | 98 | 91 | 441 | 226 | 215 | |
| 12/2/01 | BUF (0) - SF (35) | -8.5/44 | SF/U | 230 | 230 | 0 | 29 | 29 | 0 | |
| 10/4/98 | SF (21) - BUF (26) | 10/45 | BUF/O | 377 | 65 | 312 | 352 | 115 | 237 | |
| 12/3/95 | BUF (17) - SF (27) | -14/46.5 | BUF/U | 0 | 0 | 0 | 0 | 0 | 0 | |
| 9/13/92 | BUF (34) - SF (31) | -3.5/44.5 | BUF/O | 0 | 0 | 0 | 0 | 0 | 0 | |
| 12/17/89 | BUF (10) - SF (21) | -6/43.5 | SF/U | 0 | 0 | 0 | 0 | 0 | 0 | |
San Francisco Last 10
| Yards | Per Play | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Date | vs | Score | Line | ATS | Tot | Rus | Pas | Tot | Rus | Pas |
| 11/24/24 | @ GB | L 10-38 | 6/45 | L/O | -84 | -125 | 41 | 0.4 | -1.3 | 0.0 |
| 11/17/24 | SEA | L 17-20 | -6/48.5 | L/U | -12 | 37 | -49 | -0.2 | 0.8 | -0.9 |
| 11/10/24 | @ TB | W 23-20 | -6.5/50 | L/U | 198 | -35 | 233 | 3.3 | -0.7 | 5.8 |
| 10/27/24 | DAL | W 30-24 | -5.5/47.5 | W/O | 177 | 167 | 10 | 2.4 | 3.2 | 3.3 |
| 10/20/24 | KC | L 18-28 | -2/48 | L/U | -19 | -83 | 64 | 0.7 | -0.5 | 1.4 |
| 10/10/24 | @ SEA | W 36-24 | -3.5/49 | W/O | 125 | 176 | -51 | 2.9 | 4.3 | 3.2 |
| 10/6/24 | ARI | L 23-24 | -7.5/48.5 | L/U | 26 | -16 | 42 | -0.1 | -0.6 | 0.3 |
| 9/29/24 | NE | W 30-13 | -10.5/42.5 | W/O | 215 | 75 | 140 | 3.4 | 1.6 | 6.0 |
| 9/22/24 | @ LAR | L 24-27 | -6.5/45 | L/O | 129 | 39 | 90 | 0.9 | 0.3 | 2.0 |
| 9/15/24 | @ MIN | L 17-23 | -4/47 | L/U | -7 | -44 | 37 | -1.6 | -2.0 | -1.7 |
Buffalo Last 10
| Yards | Per Play | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Date | vs | Score | Line | ATS | Tot | Rus | Pas | Tot | Rus | Pas |
| 11/17/24 | KC | W 30-21 | -2.5/47 | W/O | 107 | 26 | 81 | -0.0 | -1.2 | 1.1 |
| 11/10/24 | @ IND | W 30-20 | -4.5/47 | W/O | 54 | 14 | 40 | -0.2 | -1.1 | 0.7 |
| 11/3/24 | MIA | W 30-27 | -6/49.5 | L/O | -48 | -55 | 7 | -0.7 | 0.1 | -2.1 |
| 10/27/24 | @ SEA | W 31-10 | -3/45 | W/U | 212 | 132 | 80 | 1.5 | 2.9 | 1.3 |
| 10/20/24 | TEN | W 34-10 | -10/41.5 | W/O | 100 | -15 | 115 | 2.8 | -0.0 | 4.5 |
| 10/14/24 | @ NYJ | W 23-20 | -1/42.5 | W/O | -34 | 28 | -62 | -0.8 | -1.2 | 0.6 |
| 10/6/24 | @ HOU | L 20-23 | 1/48 | L/U | -149 | 56 | -205 | -1.7 | 2.0 | -4.5 |
| 9/29/24 | @ BAL | L 10-35 | 2.5/47.5 | L/U | -191 | -190 | -1 | -3.7 | -4.4 | -3.2 |
| 9/23/24 | JAC | W 47-10 | -4.5/46.5 | W/O | 149 | 30 | 119 | 2.7 | -1.2 | 5.4 |
| 9/12/24 | @ MIA | W 31-10 | 2.5/49.5 | W/U | -104 | -31 | -73 | 0.7 | 0.1 | 1.9 |
| Abbreviations Legend |
|---|