Rookie Colin Moran had four hits, including a double, scored three runs and drove in three for the Pirates (6-1), who have won the first two games in the three-game series.
Jesse Winker had three hits and an RBI for the Reds (1-5), who were outhit 15-13.
The Pirates led just 4-2 in the sixth before Moran greeted reliever Yovani Gallardo with his third hit, a single. After Jordy Mercer doubled, Josh Harrison singled in Moran for a 5-2 lead.
Gregory Polanco followed with a walk that loaded the bases, after which Marte lined a triple to the gap in right-center, scoring all three baserunners for an 8-2 advantage.
Corey Dickerson made it a six-run inning and an eight-run lead with a two-run double two batters later.
Gallardo was pitching in relief of Reds starter Luis Castillo (0-2), who allowed four runs and six hits in five innings. He walked three and struck out three.
The Pirates piled on with four runs in the seventh for a 14-2 lead. Polanco had the big hit, a two-run double.
Trevor Williams (2-0), who pitched six innings of no-hit ball in his season debut against Detroit, got the win despite allowing 10 hits in 5 1/3 innings. He limited the Reds to two runs, walking one and striking out four.
Mercer and Dickerson had two doubles and a single apiece for the Pirates, who totaled seven extra-base hits. Marte and Harrison added two hits each.
Pirates relievers Edgar Santana, Josh Smoker and Clay Holmes combined for 3 2/3 innings of one-run relief, allowing three hits and two walks.
Castillo, batting eighth in the Reds' lineup, had two hits and scored a run. He had the club's only extra-base hit, a double.
Joey Votto and Jose Peraza also had two hits for the Reds.
--Field Level Media
Cincinnati | Pittsburgh | |
Luis Castillo | Player | Trevor Williams |
Loss | W/L | Win |
5.0 | IP | 5.1 |
3 | Strikeouts | 4 |
6 | Hits | 10 |
7.20 | ERA | 3.38 |
Cincinnati | Pittsburgh | |
Jesse Winker | Player | Colin Moran |
3 | Hits | 4 |
1 | RBI | 3 |
0 | HR | 0 |
3 | TB | 5 |
.600 | Avg | .800 |
Team | Hits | HR | TB | Avg | LOB | K | RBI | BB | SB | Errors |
Cincinnati | 13 | 0 | 14 | .351 | 23 | 6 | 3 | 3 | 0 | 1 |
Pittsburgh | 15 | 0 | 23 | .395 | 19 | 5 | 13 | 6 | 2 | 1 |