MIAMI -- Left fielder David DeJesus had several highlights, including a three-run homer, to lead the Tampa Bay Rays to an 8-5 win over the Miami Marlins on Sunday at Marlins Park.

Making just his second start of the year, DeJesus went 2-for-3 with three RBI and one diving catch. He is hitting .545 with six RBI in his 11 at-bats this season.

As a team, the Rays recorded 14 hits. Five players had multi-hit games.

The Rays (3-3) won their first series of the year, taking two of three from the slumping Marlins (1-5). Tampa Bay, which went 0-4 against Miami last season, does not meet the Marlins again until Sept. 29.

Right-hander Nathan Karns (1-1) got the win, allowing two hits, two walks and two runs, one earned, in seven innings. He struck out six.

The loss went to right-hander Henderson Alvarez (0-2), who went five innings and allowed seven hits and four runs.

Tampa Bay opened the scoring in the first. DeJesus singled and advanced to second on an error by right fielder Giancarlo Stanton. DeJesus then scored on a single by shortstop Asdrubal Cabrera.

Miami tied the score in the fourth on center fielder Ichiro Suzuki's sacrifice fly.

Left fielder Christian Yelich started the rally with a leadoff walk, and Stanton defeated the shift by beating out a slow roller to second base. Suzuki then sliced a liner to left. DeJesus charged in to make a diving catch, allowing Yelich to score but limiting the damage.

Tampa Bay jumped out to a 4-1 lead in the fifth on DeJesus' three-run homer to right-center. He hit an 0-2 pitch for his first homer of the season, although on Friday night, he had a three-run, pinch-hit double that bounced off the top of the wall at Marlins Park.

Miami cut its deficit to 4-2 in the fifth on second baseman Dee Gordon's two-out RBI triple to right-center, scoring pinch hitter Jeff Baker, who had walked.

But Tampa Bay padded its lead with two runs in the sixth. The big hits were a pinch-hit triple to center by Tim Beckham and a run-scoring double to left by catcher Rene Rivera. On the latter hit, the ball bounced off the glove of Yelich.

River added another RBI double in the eighth to increase Tampa Bay's lead to 7-2.

Miami scored twice in the bottom of the eighth on a two-out, two-run double by first baseman Michael Morse. But Ernesto Frieri, the third reliever in the inning, came on to get third baseman Donovan Solano on an inning-ending fly out to right.

Tampa Bay scored in the ninth on a two-out, two-strike single by Beckham.

Miami catcher Jarrod Saltalamacchia closed the scoring with a solo homer in the bottom of the ninth.

NOTES: Two Marlins -- CF Ichiro Suzuki and 3B Don Kelly -- made their first starts of the year. ... Kelly, however, left the game in the third inning due to a fracture of the fourth finger on his right hand and was replaced by INF Donovan Solano. ... Marlins C Jeff Mathis also left the game with the same injury. ... Suzuki got his chance when CF Marcell Ozuna arrived late to the park and was benched. The Marlins rested 3B Martin Prado, giving Kelly his opportunity. ... Kelly, 35, was a surprise addition to the 25-man roster at the end of spring training, making it due to his versatility. He is the only active player in the majors who has played all nine positions. ... Rays RHP Alex Colome (pneumonia) made his first rehab start on Saturday night, allowing three hits in three scoreless innings for the Class A Charlotte Stone Crabs. He is scheduled to pitch again for Charlotte on Thursday. ... Up next, Miami hits the road for the first time this season, opening a three-game series at Atlanta on Monday. ... Starting Monday at Toronto, the Rays' next 22 games are against AL East teams.