SEATTLE -- A Seattle Mariners bullpen that kept finding new lows hit rock bottom Saturday night when a 6-3 loss to the Chicago White Sox was followed by a roster shakeup.

Former closer Fernando Rodney, who didn't pitch in the game, was designated for assignment afterward, effectively ending his two-year career in Seattle. Rodney was an All-Star in 2014 but had fallen so far out of favor that the team finally gave up on him.

"No surprise," Rodney said. "I know when you're not doing your job. I was expecting it."

The dominoes continued to fall as reliever Danny Farquhar, who gave up three walks and a double in the 10th inning, was sent back to Triple-A Tacoma.

The White Sox used some late-inning offensive fireworks for the second game in a row, scoring five runs in the ninth and 10th to beat the Mariners and their depleted bullpen again.

"You're seeing the effects of what happens when you lose your closer," Mariners manager Lloyd McClendon said, referring to the bullpen shakeup that came when Rodney began to struggle earlier this season. "Quite frankly, guys have been thrust into roles they weren't ready for."

Rookie closer Carson Smith is the most obvious example. He struggled through another rough outing in the ninth inning, taking over with a 3-1 lead but blowing a save opportunity for the third time this month. It marked Seattle's 17th blown save of the season.

"I thought my stuff was good enough tonight to get outs," Smith said, "and I didn't have it."

The White Sox, who had piled up seven runs in the final two innings of an 11-4 win the previous night, took advantage of the struggling Seattle bullpen to improve to 11-3 in extra-inning games this season.

"We had a lot of work to do getting back in the game and tying it in the ninth," White Sox manager Robin Ventura said, "so it was a nice job by those guys."

Smith gave up two hits, a walk and two runs in the ninth. He came on to open the ninth with a 3-1 lead and allowed a single and walk to the first two batters.

Chicago shortstop Alexei Ramirez hit an RBI single up the middle, scoring Avisail Garcia from second to cut Seattle's lead to 3-2. After second baseman Carlos Sanchez sacrificed the runners to second and third, pinch-hitter Adam LaRoche drove in the tying run with a groundout to first base.

Farquhar (0-4) walked in the go-ahead run with the bases loaded in the top of the 10th and Chicago (58-63) added two unearned runs to finish off its third win in a row.

"It was a big spot," Ventura said of Garcia drawing the bases-loaded walk to bring in the winning run. "He was very patient."

Reliever Nate Jones (1-0) posted his first win of the season after getting through a scoreless ninth with back-to-back strikeouts of Seattle stars Kyle Seager and Nelson Cruz. Closer Daniel Robertson came on to pick up his 25th save of the season in the 10th.

Seattle starter Vidal Nuno turned in his longest start of the season (6 2/3 innings) while allowing one run and five hits. He hadn't made it past the fifth inning in any of his three starts since moving into the rotation from the bullpen.

Right fielder Trayce Thompson gave the White Sox a 1-0 lead with a two-out homer in the top of the second.

Seattle (56-67) was in position to tie or take the lead in the bottom of the inning, loading the bases with no outs, but the Mariners failed to score. A strikeout and inning-ending double play ended the threat.

Mariners designated hitter Nelson Cruz drew a fourth-inning walk, marking the 32nd consecutive game in which he reached base. That's the longest streak in the American League this season.

Mariners left fielder Franklin Gutierrez went 3-for-4 with two RBIs and a run scored. His two-run double in the sixth gave Seattle a 2-1 lead. Gutierrez then scored from third base on a double play for a 3-1 lead.

That inning started with a double by Cruz. Second baseman Robinson Cano reached on an error by White Sox second baseman Carlos Sanchez. Gutierrez followed with the double to left center, scoring both players, and two of the three Seattle runs in the inning ended up being unearned.

Chicago starter Carlos Rodon (5-6) gave up the one earned run, allowing six hits in seven innings. The rookie left-hander struck out eight while matching his career high of 116 pitches.

The White Sox rallied in the ninth before Farquhar came on to start the 10th and walked the first batter. Chicago first baseman Jose Abreu doubled to right-center field, setting up an intentional walk to load the bases with no outs. Farquhar then walked Garcia to bring in the go-ahead run.

In the first two games of the series, the White Sox hit .379 while scoring 12 runs in 6 1/3 innings against the Seattle bullpen.

NOTES: White Sox manager Robin Ventura compared LHP Chris Sale to Randy Johnson, saying Sale is "probably better off than Randy" was at the same stage in his career. Sale, 27, is in line to record his 1,000th career strikeout later this season, his sixth in the big leagues. Johnson also struck out 1,000 in the sixth year of his career. The 29 strikeouts by Sale in back-to-back starts were the highest two-start total of his career and the most in franchise history. ... Mariners RF Mark Trumbo was a late scratch due to a sore left knee. He will be re-evaluated on Sunday. Brad Miller replaced him in the lineup. ... Seattle RF/DH Nelson Cruz carried a 31-game streak of reaching base into the game. ... Mariners SS Ketel Marte, a rookie, went into Saturday's game with a seven-game hitting streak. ... Chicago LHP John Danks, Sunday's scheduled starter, is slated to be the fifth consecutive left-hander the Mariners will face.